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FKBP12.6 protects heart from AngII‐induced hypertrophy through inhibiting Ca(2+)/calmodulin‐mediated signalling pathways in vivo and in vitro

We previously observed that disruption of FK506‐binding protein 12.6 (FKBP12.6) gene resulted in cardiac hypertrophy in male mice. Studies showed that overexpression of FKBP12.6 attenuated thoracic aortic constriction (TAC)‐induced cardiac hypertrophy in mice, whereas the adenovirus‐mediated overexp...

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Detalles Bibliográficos
Autores principales: Xiao, Yun‐Fei, Zeng, Zhi‐Xiong, Guan, Xiao‐Hui, Wang, Ling‐Fang, Wang, Chan‐Juan, Shi, Huidong, Shou, Weinian, Deng, Ke‐Yu, Xin, Hong‐Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010737/
https://www.ncbi.nlm.nih.gov/pubmed/29682889
http://dx.doi.org/10.1111/jcmm.13645