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Endoplasmic reticulum stress induces spatial memory deficits by activating GSK‐3

Endoplasmic reticulum (ER) stress is involved in Alzheimer's disease (AD), but the mechanism is not fully understood. Here, we injected tunicamycin (TM), a recognized ER stress inducer, into the brain ventricle of Sprague‐Dawley (SD) rats to induce the unfolded protein response (UPR), demonstra...

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Detalles Bibliográficos
Autores principales: Lin, Li, Cao, Jie, Yang, Shu‐Sheng, Fu, Zheng‐Qi, Zeng, Peng, Chu, Jiang, Ning, Lin‐Na, Zhang, Teng, Shi, Yan, Tian, Qing, Zhou, Xin‐Wen, Wang, Jian‐Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010738/
https://www.ncbi.nlm.nih.gov/pubmed/29675957
http://dx.doi.org/10.1111/jcmm.13626