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NEFA‐induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non‐alcoholic steatohepatitis

The aim of this study was to investigate the changes in hepatic oxidative phosphorylation (OXPHOS) complexes (COs) in patients and cows with non‐alcoholic steatohepatitis (NASH) and to investigate the mechanism that links mitochondrial dysfunction and hepatic insulin resistance induced by non‐esteri...

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Detalles Bibliográficos
Autores principales: Gao, Wenwen, Du, Xiliang, Lei, Lin, Wang, Heyuan, Zhang, Min, Wang, Zhe, Li, Xiaobing, Liu, Guowen, Li, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010831/
https://www.ncbi.nlm.nih.gov/pubmed/29602237
http://dx.doi.org/10.1111/jcmm.13617