Cargando…

NEFA‐induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non‐alcoholic steatohepatitis

The aim of this study was to investigate the changes in hepatic oxidative phosphorylation (OXPHOS) complexes (COs) in patients and cows with non‐alcoholic steatohepatitis (NASH) and to investigate the mechanism that links mitochondrial dysfunction and hepatic insulin resistance induced by non‐esteri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Wenwen, Du, Xiliang, Lei, Lin, Wang, Heyuan, Zhang, Min, Wang, Zhe, Li, Xiaobing, Liu, Guowen, Li, Xinwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010831/ https://www.ncbi.nlm.nih.gov/pubmed/29602237 http://dx.doi.org/10.1111/jcmm.13617

Ejemplares similares

Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway
por: Li, Yu, et al.
Publicado: (2020)

Corrigendum: Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway
por: Li, Yu, et al.
Publicado: (2020)

NEFAs Influence the Inflammatory and Insulin Signaling Pathways Through TLR4 in Primary Calf Hepatocytes in vitro
por: Deng, Qinghua, et al.
Publicado: (2021)

NEFA Promotes Autophagosome Formation through Modulating PERK Signaling Pathway in Bovine Hepatocytes
por: Huang, Yan, et al.
Publicado: (2021)

Nonthermal Plasma Induces Apoptosis in ATC Cells: Involvement of JNK and p38 MAPK-Dependent ROS
por: Lee, Sei Young, et al.
Publicado: (2014)

Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway
por: Yang, Xiaorong, et al.
Publicado: (2018)

Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation
por: Zhang, Xiyu, et al.
Publicado: (2015)

Cilostazol alleviate nicotine induced cardiomyocytes hypertrophy through modulation of autophagy by CTSB/ROS/p38MAPK/JNK feedback loop
por: Wang, Shu-ya, et al.
Publicado: (2020)

Berberine Protects against NEFA-Induced Impairment of Mitochondrial Respiratory Chain Function and Insulin Signaling in Bovine Hepatocytes
por: Shi, Zhen, et al.
Publicado: (2018)

Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways
por: Jiang, Zhongjia, et al.
Publicado: (2017)

Irinotecan Induces Autophagy-Dependent Apoptosis and Positively Regulates ROS-Related JNK- and P38-MAPK Pathways in Gastric Cancer Cells
por: Zhu, Qingyun, et al.
Publicado: (2020)

Increased NEFA levels reduce blood Mg(2+) in hypertriacylglycerolaemic states via direct binding of NEFA to Mg(2+)
por: Kurstjens, Steef, et al.
Publicado: (2018)

Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals
por: Finucane, Francis M., et al.
Publicado: (2013)

Licochalcone B Induces ROS-Dependent Apoptosis in Oxaliplatin-Resistant Colorectal Cancer Cells via p38/JNK MAPK Signaling
por: Kwak, Ah-Won, et al.
Publicado: (2023)

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma
por: Pua, Lesley Jia Wei, et al.
Publicado: (2022)

Autophagy protects bone marrow mesenchymal stem cells from palmitate-induced apoptosis through the ROS-JNK/p38 MAPK signaling pathways
por: Liu, Yongyi, et al.
Publicado: (2018)

A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
por: Liu, Xin, et al.
Publicado: (2016)

Immobilization rapidly induces muscle insulin resistance together with the activation of MAPKs (JNK and p38) and impairment of AS160 phosphorylation
por: Kawamoto, Emi, et al.
Publicado: (2016)

Aprepitant Inhibits JNK and p38/MAPK to Attenuate Inflammation and Suppresses Inflammatory Pain
por: Yang, Yang, et al.
Publicado: (2022)

Downregulation of TFAM inhibits the tumorigenesis of non-small cell lung cancer by activating ROS-mediated JNK/p38MAPK signaling and reducing cellular bioenergetics
por: Xie, Deyao, et al.
Publicado: (2016)

Data on the phosphorylation of p38MAPK and JNK induced by chlorpyrifos in Drosophila melanogaster
por: Batista, J.E.S., et al.
Publicado: (2016)

Capsaicin mediates caspases activation and induces apoptosis through P38 and JNK MAPK pathways in human renal carcinoma
por: Liu, Tao, et al.
Publicado: (2016)

NEFA Dynamics in Adults With Severe Obesity and Insulin Resistance: No Coupling to the rs9939609 FTO Risk Allele
por: Mostad, Ingrid Løvold, et al.
Publicado: (2023)

The Increase of ROS Caused by the Interference of DEHP with JNK/p38/p53 Pathway as the Reason for Hepatotoxicity
por: Huang, Yuanyuan, et al.
Publicado: (2019)

Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways
por: Duan, Fengsen, et al.
Publicado: (2016)

YJI-7 Suppresses ROS Production and Expression of Inflammatory Mediators via Modulation of p38MAPK and JNK Signaling in RAW 264.7 Macrophages
por: Oh, Hye Jin, et al.
Publicado: (2018)

Picropodophyllotoxin, an Epimer of Podophyllotoxin, Causes Apoptosis of Human Esophageal Squamous Cell Carcinoma Cells Through ROS-Mediated JNK/P38 MAPK Pathways
por: Kwak, Ah-Won, et al.
Publicado: (2020)

Melatonin improves non-alcoholic fatty liver disease via MAPK-JNK/P38 signaling in high-fat-diet-induced obese mice
por: Sun, Hang, et al.
Publicado: (2016)

Potential hemo-biological identification markers to the left displaced abomasum in dairy cows
por: Song, Yuxiang, et al.
Publicado: (2020)

The activation of p38MAPK and JNK pathways in bovine herpesvirus 1 infected MDBK cells
por: Zhu, Liqian, et al.
Publicado: (2016)

Bavachinin Induces Oxidative Damage in HepaRG Cells through p38/JNK MAPK Pathways
por: Wang, Shan, et al.
Publicado: (2018)

Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency
por: Zhou, Xing-Yu, et al.
Publicado: (2021)

Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signalling pathways
por: Xu, Xingang, et al.
Publicado: (2019)

Upregulation of miR-181a impairs hepatic glucose and lipid homeostasis
por: Du, Xiliang, et al.
Publicado: (2017)

Neurotrophin3 promotes hepatocellular carcinoma apoptosis through the JNK and P38 MAPK pathways
por: Yang, Zhangshuo, et al.
Publicado: (2022)

Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
por: Chen, Xueran, et al.
Publicado: (2020)

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis
por: Gautheron, Jérémie, et al.
Publicado: (2014)

High glucose promotes annulus fibrosus cell apoptosis through activating the JNK and p38 MAPK pathways
por: Shan, Lizhen, et al.
Publicado: (2019)

ROS-Induced JNK and p38 Signaling Is Required for Unpaired Cytokine Activation during Drosophila Regeneration
por: Santabárbara-Ruiz, Paula, et al.
Publicado: (2015)

Canagliflozin Delays Aging of HUVECs Induced by Palmitic Acid via the ROS/p38/JNK Pathway
por: Hao, Wenhui, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0fgo2hjgsvrohn44hd4ej4jhro