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Common genetic variants in GAL, GAP43 and NRSN1 and interaction networks confer susceptibility to Hirschsprung disease

Hirschsprung disease (HSCR) is a severe multifactorial genetic disorder. Microarray studies indicated GAL,GAP43 and NRSN1 might contribute to the altered risk in HSCR. Thus, we focused on genetic variations in GAL,GAP43 and NRSN1, and the gene‐gene interactions involved in HSCR susceptibility. We re...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Yan, Weihui, Wang, Jun, Zhou, Ying, Chen, Jie, Gu, Beilin, Cai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010875/
https://www.ncbi.nlm.nih.gov/pubmed/29654647
http://dx.doi.org/10.1111/jcmm.13612