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Application of the CRISPR/Cas9 System to Drug Resistance in Breast Cancer
Clinical evidence indicates that drug resistance is a great obstacle in breast cancer therapy. It renders the disease uncontrollable and causes high mortality. Multiple mechanisms contribute to the development of drug resistance, but the underlying cause is usually a shift in the genetic composition...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010891/ https://www.ncbi.nlm.nih.gov/pubmed/29938175 http://dx.doi.org/10.1002/advs.201700964 |