Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma

Magnetic resonance (MR) imaging of the liver is an important tool for the detection and characterization of focal liver lesions and for assessment of diffuse liver disease, having several intrinsic characteristics, represented by high soft tissue contrast, avoidance of ionizing radiation or iodinate...

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Autores principales: Ippolito, Davide, Inchingolo, Riccardo, Grazioli, Luigi, Drago, Silvia Girolama, Nardella, Michele, Gatti, Marco, Faletti, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010944/
https://www.ncbi.nlm.nih.gov/pubmed/29930464
http://dx.doi.org/10.3748/wjg.v24.i23.2413
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author Ippolito, Davide
Inchingolo, Riccardo
Grazioli, Luigi
Drago, Silvia Girolama
Nardella, Michele
Gatti, Marco
Faletti, Riccardo
author_facet Ippolito, Davide
Inchingolo, Riccardo
Grazioli, Luigi
Drago, Silvia Girolama
Nardella, Michele
Gatti, Marco
Faletti, Riccardo
author_sort Ippolito, Davide
collection PubMed
description Magnetic resonance (MR) imaging of the liver is an important tool for the detection and characterization of focal liver lesions and for assessment of diffuse liver disease, having several intrinsic characteristics, represented by high soft tissue contrast, avoidance of ionizing radiation or iodinated contrast media, and more recently, by application of several functional imaging techniques (i.e., diffusion-weighted sequences, hepatobiliary contrast agents, perfusion imaging, magnetic resonance (MR)-elastography, and radiomics analysis). MR functional imaging techniques are extensively used both in routine practice and in the field of clinical and pre-clinical research because, through a qualitative rather than quantitative approach, they can offer valuable information about tumor tissue and tissue architecture, cellular biomarkers related to the hepatocellular functions, or tissue vascularization profiles related to tumor and tissue biology. This kind of approach offers in vivo physiological parameters, capable of evaluating physiological and pathological modifications of tissues, by the analysis of quantitative data that could be used in tumor detection, characterization, treatment selection, and follow-up, in addition to those obtained from standard morphological imaging. In this review we provide an overview of recent advanced techniques in MR for the diagnosis and staging of hepatocellular carcinoma, and their role in the assessment of response treatment evaluation.
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spelling pubmed-60109442018-06-21 Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma Ippolito, Davide Inchingolo, Riccardo Grazioli, Luigi Drago, Silvia Girolama Nardella, Michele Gatti, Marco Faletti, Riccardo World J Gastroenterol Review Magnetic resonance (MR) imaging of the liver is an important tool for the detection and characterization of focal liver lesions and for assessment of diffuse liver disease, having several intrinsic characteristics, represented by high soft tissue contrast, avoidance of ionizing radiation or iodinated contrast media, and more recently, by application of several functional imaging techniques (i.e., diffusion-weighted sequences, hepatobiliary contrast agents, perfusion imaging, magnetic resonance (MR)-elastography, and radiomics analysis). MR functional imaging techniques are extensively used both in routine practice and in the field of clinical and pre-clinical research because, through a qualitative rather than quantitative approach, they can offer valuable information about tumor tissue and tissue architecture, cellular biomarkers related to the hepatocellular functions, or tissue vascularization profiles related to tumor and tissue biology. This kind of approach offers in vivo physiological parameters, capable of evaluating physiological and pathological modifications of tissues, by the analysis of quantitative data that could be used in tumor detection, characterization, treatment selection, and follow-up, in addition to those obtained from standard morphological imaging. In this review we provide an overview of recent advanced techniques in MR for the diagnosis and staging of hepatocellular carcinoma, and their role in the assessment of response treatment evaluation. Baishideng Publishing Group Inc 2018-06-21 2018-06-21 /pmc/articles/PMC6010944/ /pubmed/29930464 http://dx.doi.org/10.3748/wjg.v24.i23.2413 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Review
Ippolito, Davide
Inchingolo, Riccardo
Grazioli, Luigi
Drago, Silvia Girolama
Nardella, Michele
Gatti, Marco
Faletti, Riccardo
Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma
title Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma
title_full Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma
title_fullStr Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma
title_full_unstemmed Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma
title_short Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma
title_sort recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010944/
https://www.ncbi.nlm.nih.gov/pubmed/29930464
http://dx.doi.org/10.3748/wjg.v24.i23.2413
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