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A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma
Over the past decade, therapies targeting the VEGF/VEGFR and mTOR pathways have served as the standard of care for the clinical management of renal cell carcinoma (RCC) patients. Albeit promising, these targeted drugs have attained only modest clinical benefits with limited prolonged progression-fre...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010995/ https://www.ncbi.nlm.nih.gov/pubmed/29930727 http://dx.doi.org/10.7150/thno.23964 |