Cargando…
A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma
Over the past decade, therapies targeting the VEGF/VEGFR and mTOR pathways have served as the standard of care for the clinical management of renal cell carcinoma (RCC) patients. Albeit promising, these targeted drugs have attained only modest clinical benefits with limited prolonged progression-fre...
Autores principales: | Sun, Jingya, Wang, Xin, Tang, Boyun, Liu, Hongchun, Zhang, Minmin, Wang, Yueqin, Ping, Fangfang, Ding, Jian, Shen, Aijun, Geng, Meiyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010995/ https://www.ncbi.nlm.nih.gov/pubmed/29930727 http://dx.doi.org/10.7150/thno.23964 |
Ejemplares similares
-
Identification and Therapeutic Intervention of Coactivated Anaplastic Lymphoma Kinase, Fibroblast Growth Factor Receptor 2, and Ephrin Type‐A Receptor 5 Kinases in Hepatocellular Carcinoma
por: Wang, Xin, et al.
Publicado: (2018) -
Dasatinib targets c-Src kinase in cardiotoxicity
por: Elmadani, Manar, et al.
Publicado: (2023) -
The Biology and Therapeutic Potential of the Src-YAP Axis in Non-Small Cell Lung Cancer (NSCLC)
por: Papavassiliou, Kostas A., et al.
Publicado: (2022) -
SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis
por: Lamar, John M., et al.
Publicado: (2019) -
Chromopeptide A, a highly cytotoxic depsipeptide from the marine sediment-derived bacterium Chromobacterium sp. HS-13-94
por: Zhou, Zhenfang, et al.
Publicado: (2015)