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CD38 Deficiency Promotes Inflammatory Response through Activating Sirt1/NF-κB-Mediated Inhibition of TLR2 Expression in Macrophages

CD38 was first identified as a lymphocyte-specific antigen and then has been found to be widely expressed in a variety of cell types. The functions of CD38 are involved in numerous biological processes including immune responses. Here, we showed the downregulations of both TLR2 mRNA and protein in m...

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Detalles Bibliográficos
Autores principales: Qian, Yisong, Chen, Chuqiao, Ma, Leliang, Wang, Ziwei, Wang, Ling-Fang, Zuo, Li, Yang, Yaqin, Huang, Xiang, Jiang, Meixiu, Wang, Xiaolei, Shi, Huidong, Fu, Mingui, Deng, Ke-Yu, Xin, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011090/
https://www.ncbi.nlm.nih.gov/pubmed/29977153
http://dx.doi.org/10.1155/2018/8736949