Characterization of Atherosclerosis Formation in a Murine Model of Type IIa Human Familial Hypercholesterolemia

A murine genetic model of LDL-cholesterol- (LDL-C-) driven atherosclerosis, based on complete deficiencies of both the LDL-receptor (Ldlr(−/−)) and key catalytic component of an apolipoprotein B-edisome complex (Apobec1(−/−)), which converts apoB-100 to apoB-48, has been extensively characterized. T...

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Detalles Bibliográficos
Autores principales: Miyajima, Chiharu, Iwaki, Takayuki, Umemura, Kazuo, Ploplis, Victoria A., Castellino, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011105/
https://www.ncbi.nlm.nih.gov/pubmed/29977908
http://dx.doi.org/10.1155/2018/1878964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011105/
https://www.ncbi.nlm.nih.gov/pubmed/29977908
http://dx.doi.org/10.1155/2018/1878964

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