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Geminin Orchestrates Somite Formation by Regulating Fgf8 and Notch Signaling

During somitogenesis, Fgf8 maintains the predifferentiation stage of presomitic mesoderm (PSM) cells and its retraction gives a cue for somite formation. Delta/Notch initiates the expression of oscillation genes in the tail bud and subsequently contributes to somite formation in a periodic way. Whet...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Zhang, Yu, Cao, Kang, Luo, Lingfei, Huang, Sizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011172/
https://www.ncbi.nlm.nih.gov/pubmed/29984243
http://dx.doi.org/10.1155/2018/6543196