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The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU

[Image: see text] The biosynthetic pathway of peptidoglycan is essential for Mycobacterium tuberculosis. We report here the acetyltransferase substrate specificity and catalytic mechanism of the bifunctional N-acetyltransferase/uridylyltransferase from M. tuberculosis (GlmU). This enzyme is responsi...

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Detalles Bibliográficos
Autores principales: Craggs, Peter D., Mouilleron, Stephane, Rejzek, Martin, de Chiara, Cesira, Young, Robert J., Field, Robert A., Argyrou, Argyrides, de Carvalho, Luiz Pedro S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011181/
https://www.ncbi.nlm.nih.gov/pubmed/29684272
http://dx.doi.org/10.1021/acs.biochem.8b00121