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iTRAQ-Based Proteomic Analysis reveals possible target-related proteins and signal networks in human osteoblasts overexpressing FGFR2

BACKGROUND: Fibroblast growth factor receptor 2 (FGFR2) play a vital role in skeletogenesis. However, the molecular mechanisms triggered by FGFR2 in osteoblasts are still not fully understood. In this study, proteomics and bioinformatics analysis were performed to investigate changes in the protein...

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Detalles Bibliográficos
Autores principales: Cai, Tianyi, Wu, Baojin, Tang, Xinjie, Zhou, Zhaoping, Yang, Junyi, Ke, Ronghu, Mu, Xiongzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011184/
https://www.ncbi.nlm.nih.gov/pubmed/29950929
http://dx.doi.org/10.1186/s12953-018-0140-x