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iTRAQ-Based Proteomic Analysis reveals possible target-related proteins and signal networks in human osteoblasts overexpressing FGFR2
BACKGROUND: Fibroblast growth factor receptor 2 (FGFR2) play a vital role in skeletogenesis. However, the molecular mechanisms triggered by FGFR2 in osteoblasts are still not fully understood. In this study, proteomics and bioinformatics analysis were performed to investigate changes in the protein...
Autores principales: | Cai, Tianyi, Wu, Baojin, Tang, Xinjie, Zhou, Zhaoping, Yang, Junyi, Ke, Ronghu, Mu, Xiongzheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011184/ https://www.ncbi.nlm.nih.gov/pubmed/29950929 http://dx.doi.org/10.1186/s12953-018-0140-x |
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