Cargando…

Combating head and neck cancer metastases by targeting Src using multifunctional nanoparticle-based saracatinib

BACKGROUND: Inhibition of metastasis of head and neck squamous cell carcinoma (HNSCC) is one of the most important challenges in cancer treatment. Src, a non-receptor tyrosine kinase, has been implicated as a key promoter in tumor progression and metastasis of HNSCC. However, Src therapy for HNSCC i...

Descripción completa

Detalles Bibliográficos
Autores principales: Lang, Liwei, Shay, Chloe, Xiong, Yuanping, Thakkar, Parth, Chemmalakuzhy, Ron, Wang, Xuli, Teng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011403/
https://www.ncbi.nlm.nih.gov/pubmed/29925404
http://dx.doi.org/10.1186/s13045-018-0623-3