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Combating head and neck cancer metastases by targeting Src using multifunctional nanoparticle-based saracatinib
BACKGROUND: Inhibition of metastasis of head and neck squamous cell carcinoma (HNSCC) is one of the most important challenges in cancer treatment. Src, a non-receptor tyrosine kinase, has been implicated as a key promoter in tumor progression and metastasis of HNSCC. However, Src therapy for HNSCC i...
Autores principales: | Lang, Liwei, Shay, Chloe, Xiong, Yuanping, Thakkar, Parth, Chemmalakuzhy, Ron, Wang, Xuli, Teng, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011403/ https://www.ncbi.nlm.nih.gov/pubmed/29925404 http://dx.doi.org/10.1186/s13045-018-0623-3 |
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