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Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons

Dopamine plays a key role in the cellular and behavioral responses to drugs of abuse, but the implication of metabotropic regulatory input to dopaminergic neurons on acute drug effects and subsequent drug-related behavior remains unclear. Here, we used chemogenetics [Designer Receptors Exclusively A...

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Detalles Bibliográficos
Autores principales: Runegaard, Annika H., Sørensen, Andreas T., Fitzpatrick, Ciarán M., Jørgensen, Søren H., Petersen, Anders V., Hansen, Nikolaj W., Weikop, Pia, Andreasen, Jesper T., Mikkelsen, Jens D., Perrier, Jean-Francois, Woldbye, David, Rickhag, Mattias, Wortwein, Gitta, Gether, Ulrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011418/
https://www.ncbi.nlm.nih.gov/pubmed/29938215
http://dx.doi.org/10.1523/ENEURO.0345-17.2018