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Mitochondrial DNA mutations associated with aminoglycoside induced ototoxicity

Aminoglycosides (AmAn) are widely used for their great efficiency against gram-negative bacterial infections. However, they can also induce ototoxic hearing loss, which has affected millions of people around the world. As previously reported, individuals bearing mitochondrial DNA mutations in the 12...

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Detalles Bibliográficos
Autores principales: Gao, Zewen, Chen, Ye, Guan, Min-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese PLA General Hospital 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011804/
https://www.ncbi.nlm.nih.gov/pubmed/29937831
http://dx.doi.org/10.1016/j.joto.2017.02.001