Machine-learned analysis of the association of next-generation sequencing–based human TRPV1 and TRPA1 genotypes with the sensitivity to heat stimuli and topically applied capsaicin

Heat pain and its modulation by capsaicin varies among subjects in experimental and clinical settings. A plausible cause is a genetic component, of which TRPV1 ion channels, by their response to both heat and capsaicin, are primary candidates. However, TRPA1 channels can heterodimerize with TRPV1 ch...

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Detalles Bibliográficos
Autores principales: Kringel, Dario, Geisslinger, Gerd, Resch, Eduard, Oertel, Bruno G., Thrun, Michael C., Heinemann, Sarah, Lötsch, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012053/
https://www.ncbi.nlm.nih.gov/pubmed/29596157
http://dx.doi.org/10.1097/j.pain.0000000000001222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012053/
https://www.ncbi.nlm.nih.gov/pubmed/29596157
http://dx.doi.org/10.1097/j.pain.0000000000001222

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