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Adoptive Transfer of Interleukin-21-stimulated Human CD8(+) T Memory Stem Cells Efficiently Inhibits Tumor Growth

Memory stem T (T(SCM)) cells, a new subset of memory T cells with self-renewal and multipotent capacities, are considered as a promising candidates for adoptive cellular therapy. However, the low proportion of human T(SCM) cells in total CD8(+) T cells limits their utility. Here, we aimed to induce...

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Detalles Bibliográficos
Autores principales: Chen, Yingshi, Yu, Fei, Jiang, Yawen, Chen, Jingliang, Wu, Kang, Chen, Xinxin, Lin, Yingtong, Zhang, Hui, Li, Linghua, Zhang, Yiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012057/
https://www.ncbi.nlm.nih.gov/pubmed/29864078
http://dx.doi.org/10.1097/CJI.0000000000000229