Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis

In response to collagen stimulation, platelets use a coordinated system of fluid entry to undergo membrane ballooning, procoagulant spreading, and microvesiculation. We hypothesized that water entry was mediated by the water channel aquaporin-1 (AQP1) and aimed to determine its role in the platelet...

Descripción completa

Detalles Bibliográficos
Autores principales: Agbani, Ejaife O., Williams, Christopher M., Li, Yong, van den Bosch, Marion T.J., Moore, Samantha F., Mauroux, Adele, Hodgson, Lorna, Verkman, Alan S., Hers, Ingeborg, Poole, Alastair W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012506/
https://www.ncbi.nlm.nih.gov/pubmed/29769447
http://dx.doi.org/10.1172/jci.insight.99062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012506/
https://www.ncbi.nlm.nih.gov/pubmed/29769447
http://dx.doi.org/10.1172/jci.insight.99062

Ejemplares similares