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Clonal evolution of colorectal cancer in a patient with serially resected metastases and liquid biopsies: a case report and discussion of the literature

BACKGROUND: Metastatic colorectal cancer represents a striking example of clonal heterogeneity and tumour evolution, which generates acquired resistance to therapy. Once hard to perform, the study of clonal heterogeneity is now significantly aided by the use of liquid biopsies. METHOD: We herein rep...

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Detalles Bibliográficos
Autores principales: Kastrisiou, Myrto, Zarkavelis, George, Kampletsas, Eleftherios, Panopoulou, Eleni, Goussia, Anna, Nasioulas, George, Papadopoulou, Eirini, Tsaousi, Christina, Pentheroudakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012565/
https://www.ncbi.nlm.nih.gov/pubmed/29942663
http://dx.doi.org/10.1136/esmoopen-2018-000329