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Clonal evolution of colorectal cancer in a patient with serially resected metastases and liquid biopsies: a case report and discussion of the literature
BACKGROUND: Metastatic colorectal cancer represents a striking example of clonal heterogeneity and tumour evolution, which generates acquired resistance to therapy. Once hard to perform, the study of clonal heterogeneity is now significantly aided by the use of liquid biopsies. METHOD: We herein rep...
Autores principales: | Kastrisiou, Myrto, Zarkavelis, George, Kampletsas, Eleftherios, Panopoulou, Eleni, Goussia, Anna, Nasioulas, George, Papadopoulou, Eirini, Tsaousi, Christina, Pentheroudakis, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012565/ https://www.ncbi.nlm.nih.gov/pubmed/29942663 http://dx.doi.org/10.1136/esmoopen-2018-000329 |
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