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Modelling of the breadth of expression from promoter architectures identifies pro-housekeeping transcription factors
Understanding how regulatory elements control mammalian gene expression is a challenge of post-genomic era. We previously reported that size of proximal promoter architecture predicted the breadth of expression (fraction of tissues in which a gene is expressed). Herein, the contributions of individu...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013173/ https://www.ncbi.nlm.nih.gov/pubmed/29928029 http://dx.doi.org/10.1371/journal.pone.0198961 |