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Modelling of the breadth of expression from promoter architectures identifies pro-housekeeping transcription factors

Understanding how regulatory elements control mammalian gene expression is a challenge of post-genomic era. We previously reported that size of proximal promoter architecture predicted the breadth of expression (fraction of tissues in which a gene is expressed). Herein, the contributions of individu...

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Detalles Bibliográficos
Autor principal: Huminiecki, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013173/
https://www.ncbi.nlm.nih.gov/pubmed/29928029
http://dx.doi.org/10.1371/journal.pone.0198961