A novel epigenetic modulating agent sensitizes pancreatic cells to a chemotherapy agent

Pancreatic ductal adenocarcinoma (PDAC) is expected to be the second leading cause of cancer mortality by 2030. PDAC remains resistant to the majority of systemic chemotherapies. In this paper, we explore if epigenetic sensitization can improve chemotherapy response in PDAC. Multiple PDAC cell lines...

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Detalles Bibliográficos
Autores principales: Thakar, Manjusha, Hu, Yue, Morreale, Michael, Lerner, Lane, Ying Lin, Wan, Sen, Rupashree, Cai, Yi, Karunasena, Enusha, Thakar, Maya, Saggi, Soren, Keer, Harold, Ahuja, Nita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013229/
https://www.ncbi.nlm.nih.gov/pubmed/29927979
http://dx.doi.org/10.1371/journal.pone.0199130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013229/
https://www.ncbi.nlm.nih.gov/pubmed/29927979
http://dx.doi.org/10.1371/journal.pone.0199130

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