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A novel epigenetic modulating agent sensitizes pancreatic cells to a chemotherapy agent
Pancreatic ductal adenocarcinoma (PDAC) is expected to be the second leading cause of cancer mortality by 2030. PDAC remains resistant to the majority of systemic chemotherapies. In this paper, we explore if epigenetic sensitization can improve chemotherapy response in PDAC. Multiple PDAC cell lines...
Autores principales: | Thakar, Manjusha, Hu, Yue, Morreale, Michael, Lerner, Lane, Ying Lin, Wan, Sen, Rupashree, Cai, Yi, Karunasena, Enusha, Thakar, Maya, Saggi, Soren, Keer, Harold, Ahuja, Nita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013229/ https://www.ncbi.nlm.nih.gov/pubmed/29927979 http://dx.doi.org/10.1371/journal.pone.0199130 |
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