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DENR–MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation

The succession of molecular events leading to eukaryotic translation reinitiation—whereby ribosomes terminate translation of a short open reading frame (ORF), resume scanning, and then translate a second ORF on the same mRNA—is not well understood. Density-regulated reinitiation and release factor (...

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Detalles Bibliográficos
Autores principales: Ahmed, Yasar Luqman, Schleich, Sibylle, Bohlen, Jonathan, Mandel, Nicolas, Simon, Bernd, Sinning, Irmgard, Teleman, Aurelio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013234/
https://www.ncbi.nlm.nih.gov/pubmed/29889857
http://dx.doi.org/10.1371/journal.pbio.2005160