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BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity

The mesodermal germ layer is patterned into mediolateral subtypes by signaling factors including BMP and FGF. How these pathways are integrated to induce specific mediolateral cell fates is not well understood. We used mesoderm derived from post-gastrulation neuromesodermal progenitors (NMPs), which...

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Detalles Bibliográficos
Autores principales: Row, Richard H, Pegg, Amy, Kinney, Brian A, Farr, Gist H, Maves, Lisa, Lowell, Sally, Wilson, Valerie, Martin, Benjamin L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013256/
https://www.ncbi.nlm.nih.gov/pubmed/29877796
http://dx.doi.org/10.7554/eLife.31018