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Metabotropic glutamate receptor subtype 3 gates acute stress-induced dysregulation of amygdalo-cortical function

Stress can precipitate or worsen symptoms of many psychiatric disorders by dysregulating glutamatergic function within the prefrontal cortex (PFC). Previous studies suggest that antagonists of group II metabotropic glutamate (mGlu) receptors (mGlu(2) and mGlu(3)) reduce stress-induced anhedonia thro...

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Detalles Bibliográficos
Autores principales: Joffe, Max E., Santiago, Chiaki I., Engers, Julie L., Lindsley, Craig W., Conn, P. Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013320/
https://www.ncbi.nlm.nih.gov/pubmed/29269844
http://dx.doi.org/10.1038/s41380-017-0015-z