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Krüppel-Like Factor 10 participates in cervical cancer immunoediting through transcriptional regulation of Pregnancy-Specific Beta-1 Glycoproteins

Cervical cancer (CC) is associated with alterations in immune system balance, which is primarily due to a shift from Th1 to Th2 and the unbalance of Th17/Treg cells. Using in silico DNA copy number analysis, we have demonstrated that ~20% of CC samples exhibit gain of 8q22.3 and 19q13.31; the region...

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Detalles Bibliográficos
Autores principales: Marrero-Rodríguez, Daniel, Taniguchi-Ponciano, Keiko, Subramaniam, Malayannan, Hawse, John R., Pitel, Kevin S., Arreola-De la Cruz, Hugo, Huerta-Padilla, Victor, Ponce-Navarrete, Gustavo, Figueroa-Corona, Ma. del Pilar, Gomez-Virgilio, Laura, Martinez-Cuevas, Teresa I., Mendoza-Rodriguez, Monica, Rodriguez-Esquivel, Miriam, Romero-Morelos, Pablo, Ramirez-Salcedo, Jorge, Baudis, Michael, Meraz-Rios, Marco, Jimenez-Vega, Florinda, Salcedo, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013423/
https://www.ncbi.nlm.nih.gov/pubmed/29930344
http://dx.doi.org/10.1038/s41598-018-27711-8