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Acetylcholine-modulated plasticity in reward-driven navigation: a computational study

Neuromodulation plays a fundamental role in the acquisition of new behaviours. In previous experimental work, we showed that acetylcholine biases hippocampal synaptic plasticity towards depression, and the subsequent application of dopamine can retroactively convert depression into potentiation. We...

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Detalles Bibliográficos
Autores principales: Zannone, Sara, Brzosko, Zuzanna, Paulsen, Ole, Clopath, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013476/
https://www.ncbi.nlm.nih.gov/pubmed/29930322
http://dx.doi.org/10.1038/s41598-018-27393-2