A novel MLH1 mutation in a Japanese family with Lynch syndrome associated with small bowel cancer

Lynch syndrome is a genetic disorder related to cancer predisposition, including colorectal cancer, endometrial cancer, and ovarian cancer. Germline mutations in mismatch repair genes, including MLH1, MSH2, MSH6, and PMS2, are responsible for this condition. Cancer tissue specimens resected from sma...

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Detalles Bibliográficos
Autores principales: Akizawa, Yoshika, Yamamoto, Toshiyuki, Tamura, Kazuo, Kanno, Toshiyuki, Takahashi, Nobuko, Ohki, Takeshi, Omori, Teppei, Tokushige, Katsutoshi, Yamamoto, Masakazu, Saito, Kayoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Data Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013486/
https://www.ncbi.nlm.nih.gov/pubmed/30083359
http://dx.doi.org/10.1038/s41439-018-0013-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013486/
https://www.ncbi.nlm.nih.gov/pubmed/30083359
http://dx.doi.org/10.1038/s41439-018-0013-y

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