Systemic Acrolein Elevations in Mice With Experimental Autoimmune Encephalomyelitis and Patients With Multiple Sclerosis

Demyelination and axonal injury are the key pathological processes in multiple sclerosis (MS), driven by inflammation and oxidative stress. Acrolein, a byproduct and instigator of oxidative stress, has been demonstrated as a neurotoxin in experimental autoimmune encephalomyelitis (EAE), an animal mo...

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Detalles Bibliográficos
Autores principales: Tully, Melissa, Tang, Jonathan, Zheng, Lingxing, Acosta, Glen, Tian, Ran, Hayward, Lee, Race, Nicholas, Mattson, David, Shi, Riyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013577/
https://www.ncbi.nlm.nih.gov/pubmed/29963001
http://dx.doi.org/10.3389/fneur.2018.00420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013577/
https://www.ncbi.nlm.nih.gov/pubmed/29963001
http://dx.doi.org/10.3389/fneur.2018.00420

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