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Further Characterization of the Capsule-Like Complex (CLC) Produced by Francisella tularensis Subspecies tularensis: Protective Efficacy and Similarity to Outer Membrane Vesicles

Francisella tularensis is the etiologic agent of tularemia, and subspecies tularensis (type A) is the most virulent subspecies. The live vaccine strain (LVS) of subspecies holarctica produces a capsule-like complex (CLC) that consists of a large variety of glycoproteins. Expression of the CLC is gre...

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Detalles Bibliográficos
Autores principales: Champion, Anna E., Bandara, Aloka B., Mohapatra, Nrusingh, Fulton, Kelly M., Twine, Susan M., Inzana, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013578/
https://www.ncbi.nlm.nih.gov/pubmed/29963499
http://dx.doi.org/10.3389/fcimb.2018.00182