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Correlates of Protection Against SIV(mac251) Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors

We report on prime-boost vaccine regimens with two simian adenovirus (Ad) vectors (SAdV) or two human serotype Ad vectors (HAdV) expressing Gag and gp160 of simian immunodeficiency virus (SIV)(mac239) tested in HAdV-seropositive rhesus macaques (RMs) repeatedly challenged rectally with low doses of...

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Detalles Bibliográficos
Autores principales: Tuyishime, Steven, Haut, Larissa H., Kurupati, Raj K., Billingsley, James M., Carnathan, Diane, Gangahara, Sailaja, Styles, Tiffany M., Xiang, ZhiQuan, Li, Yan, Zopfs, Malte, Liu, Qin, Zhou, XiangYang, Lewis, Mark G., Amara, Rama R., Bosinger, Steven, Silvestri, Guido, Ertl, Hildegund C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013748/
https://www.ncbi.nlm.nih.gov/pubmed/29685793
http://dx.doi.org/10.1016/j.ebiom.2018.02.025