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Effect of Trinucleotide Repeats in the Huntington's Gene on Intelligence

BACKGROUND: Huntington's Disease (HD) is caused by an abnormality in the HTT gene. This gene includes trinucleotide repeats ranging from 10 to 35, and when expanded beyond 39, causes HD. We previously reported that CAG repeats in the normal range had a direct and beneficial effect on brain deve...

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Detalles Bibliográficos
Autores principales: Lee, Jessica K., Conrad, Amy, Epping, Eric, Mathews, Kathy, Magnotta, Vincent, Dawson, Jeffrey D., Nopoulos, Peg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013750/
https://www.ncbi.nlm.nih.gov/pubmed/29685790
http://dx.doi.org/10.1016/j.ebiom.2018.03.031