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Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents

Somatic mutations contribute to the heterogeneous prognosis of chronic myelomonocytic leukemia (CMML). Hypomethylating agents (HMAs) are active in CMML, but analyses of small series failed to identify mutations predicting response or survival. We analyzed a retrospective multi-center cohort of 174 C...

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Detalles Bibliográficos
Autores principales: Duchmann, Matthieu, Yalniz, Fevzi F., Sanna, Alessandro, Sallman, David, Coombs, Catherine C., Renneville, Aline, Kosmider, Olivier, Braun, Thorsten, Platzbecker, Uwe, Willems, Lise, Adès, Lionel, Fontenay, Michaela, Rampal, Raajit, Padron, Eric, Droin, Nathalie, Preudhomme, Claude, Santini, Valeria, Patnaik, Mrinal M., Fenaux, Pierre, Solary, Eric, Itzykson, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013781/
https://www.ncbi.nlm.nih.gov/pubmed/29728305
http://dx.doi.org/10.1016/j.ebiom.2018.04.018