Delivering the cell-impermeable DNA ‘light-switching’ Ru(ii) complexes preferentially into live-cell nucleus via an unprecedented ion-pairing method

The dipyridophenazine (dppz) based ruthenium polypyridyl complexes are known as molecular ‘light-switches’ for DNA. This property is poised to serve in diagnostic and therapeutic applications, but the poor cellular uptake restricts their use in live cells. Herein, we show that the cellular uptake, a...

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Detalles Bibliográficos
Autores principales: Zhu, Ben-Zhan, Chao, Xi-Juan, Huang, Chun-Hua, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013783/
https://www.ncbi.nlm.nih.gov/pubmed/30155044
http://dx.doi.org/10.1039/c5sc03796d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013783/
https://www.ncbi.nlm.nih.gov/pubmed/30155044
http://dx.doi.org/10.1039/c5sc03796d

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