A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

Human gene-2 relaxin (H2 relaxin) is a pleiotropic hormone with powerful vasodilatory and anti-fibrotic properties which has led to its clinical evaluation and provisional FDA approval as a treatment for acute heart failure. The diverse effects of H2 relaxin are mediated via its cognate G protein co...

Descripción completa

Detalles Bibliográficos
Autores principales: Hossain, Mohammed Akhter, Kocan, Martina, Yao, Song T., Royce, Simon G., Nair, Vinojini B., Siwek, Christopher, Patil, Nitin A., Harrison, Ian P., Rosengren, K. Johan, Selemidis, Stavros, Summers, Roger J., Wade, John D., Bathgate, Ross A. D., Samuel, Chrishan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013806/
https://www.ncbi.nlm.nih.gov/pubmed/30155023
http://dx.doi.org/10.1039/c5sc04754d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013806/
https://www.ncbi.nlm.nih.gov/pubmed/30155023
http://dx.doi.org/10.1039/c5sc04754d

Ejemplares similares