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Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer

BACKGROUND: Almost all of the extracellular matrix (ECM) components can be degraded by the endoproteinases matrix metalloproteinases (MMPs). Important regulators of MMPs, and thereby of the extracellular environment, are tissue inhibitors of metalloproteinases (TIMPs), and especially TIMP-1. Early t...

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Detalles Bibliográficos
Autores principales: Böckelman, Camilla, Beilmann-Lehtonen, Ines, Kaprio, Tuomas, Koskensalo, Selja, Tervahartiala, Taina, Mustonen, Harri, Stenman, Ulf-Håkan, Sorsa, Timo, Haglund, Caj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013876/
https://www.ncbi.nlm.nih.gov/pubmed/29929486
http://dx.doi.org/10.1186/s12885-018-4589-x