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Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice

Bifurcation of axons from dorsal root ganglion (DRG) and cranial sensory ganglion (CSG) neurons is mediated by a cGMP-dependent signaling pathway composed of the ligand C-type natriuretic peptide (CNP), the receptor guanylyl cyclase Npr2 and the cGMP-dependent protein kinase I (cGKI). Here, we demon...

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Detalles Bibliográficos
Autores principales: Ter-Avetisyan, Gohar, Dumoulin, Alexandre, Herrel, Anthony, Schmidt, Hannes, Strump, Johanna, Afzal, Shoaib, Rathjen, Fritz G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013911/
https://www.ncbi.nlm.nih.gov/pubmed/29962937
http://dx.doi.org/10.3389/fncel.2018.00153