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Computational analysis of mRNA expression profiling in the inner ear reveals candidate transcription factors associated with proliferation, differentiation, and deafness

BACKGROUND: Hearing loss is a major cause of disability worldwide, impairing communication, health, and quality of life. Emerging methods of gene therapy aim to address this morbidity, which can be employed to fix a genetic problem causing hair cell dysfunction and to promote the proliferation of su...

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Detalles Bibliográficos
Autores principales: Perl, Kobi, Shamir, Ron, Avraham, Karen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013912/
https://www.ncbi.nlm.nih.gov/pubmed/29929553
http://dx.doi.org/10.1186/s40246-018-0161-7