Diastereoselective synthesis of vicinal tertiary and N-substituted quaternary stereogenic centers by catalytic hydroalkylation of dienes

An efficient and diastereoselective (CDC)–Rh-catalyzed hydroalkylation of dienes with 1,3-oxazol-5(4H)-ones is reported. Aryl and alkyl substituted dienes are converted to α,α-substituted oxazolones (24 examples) by the formation of N-substituted quaternary carbon stereogenic centers in good yields...

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Detalles Bibliográficos
Autores principales: Goldfogel, Matthew J., Meek, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013916/
https://www.ncbi.nlm.nih.gov/pubmed/30155052
http://dx.doi.org/10.1039/c5sc04908c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013916/
https://www.ncbi.nlm.nih.gov/pubmed/30155052
http://dx.doi.org/10.1039/c5sc04908c

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