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Self-assembly of nucleic acid molecular aggregates catalyzed by a triple-helix probe for miRNA detection and single cell imaging

We herein report a novel finding that nucleic acid molecular aggregates (NAMAs) self-assembled on graphene oxide nanoplates (GONPs) as a result of DNA rolling circle amplification (RCA) and a functionalized triple-helix probe (THP) in single cells. The functionalized THP containing the aptamer regio...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Wang, Yuanyuan, Zhang, Ningbo, Zhang, Shusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013927/
https://www.ncbi.nlm.nih.gov/pubmed/30155063
http://dx.doi.org/10.1039/c6sc00694a