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Higher levels of thyroxine may predict a favorable response to donepezil treatment in patients with Alzheimer disease: a prospective, case–control study

BACKGROUND: Cholinergic hypothesis has been advanced as an etiology of Alzheimer disease (AD) on the basis of the presynaptic deficit found in the diseased brains, and cholinesterase inhibitors (ChEIs) are the treatment of choice for these patients. However, only about half of treatment efficacy was...

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Detalles Bibliográficos
Autores principales: Chang, Yu San, Wu, Yu Hsuan, Wang, Chin Jen, Tang, Shu Hui, Chen, Hsiang Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013955/
https://www.ncbi.nlm.nih.gov/pubmed/29929471
http://dx.doi.org/10.1186/s12868-018-0436-x