A Chinese family affected by lynch syndrome caused by MLH1 mutation

BACKGROUND: Lynch syndrome (LS) is caused by mutations in DNA mismatch repair (MMR) genes, which accounts for 3–5% of colorectal cancer. The risks of several types of cancer are greatly increased among individuals with LS. In this study, 4 members of a Chinese family with a MLH1 pathogenic variant,...

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Detalles Bibliográficos
Autores principales: Jia, Shuqin, Zhang, Meng, Sun, Yu, Yan, Hai, Zhao, Fangping, Li, Ziyu, Ji, Jiafu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014015/
https://www.ncbi.nlm.nih.gov/pubmed/29929473
http://dx.doi.org/10.1186/s12881-018-0605-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014015/
https://www.ncbi.nlm.nih.gov/pubmed/29929473
http://dx.doi.org/10.1186/s12881-018-0605-x

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