Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders

Accumulation of aggregated α-synuclein into Lewy bodies is thought to contribute to the onset and progression of dopaminergic neuron degeneration in Parkinson's disease (PD) and related disorders. Although protein aggregation is associated with perturbation of proteostasis, how α-synuclein aggr...

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Detalles Bibliográficos
Autores principales: Ugras, Scott, Daniels, Malcolm J., Fazelinia, Hossein, Gould, Neal S., Yocum, Anastasia K., Luk, Kelvin C., Luna, Esteban, Ding, Hua, McKennan, Chris, Seeholzer, Steven, Martinez, Dan, Evans, Perry, Brown, Daniel, Duda, John E., Ischiropoulos, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014061/
https://www.ncbi.nlm.nih.gov/pubmed/29759483
http://dx.doi.org/10.1016/j.ebiom.2018.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014061/
https://www.ncbi.nlm.nih.gov/pubmed/29759483
http://dx.doi.org/10.1016/j.ebiom.2018.05.007

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