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Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice
BACKGROUND: Immunoglobulin(Ig)E-associated allergies result from misguided immune responses against innocuous antigens. CD4(+) T lymphocytes are critical for initiating and perpetuating that process, yet the crucial factors determining whether an individual becomes sensitized towards a given allerge...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014064/ https://www.ncbi.nlm.nih.gov/pubmed/29678672 http://dx.doi.org/10.1016/j.ebiom.2018.04.001 |