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Spindle assembly checkpoint strength is linked to cell fate in the Caenorhabditis elegans embryo
The spindle assembly checkpoint (SAC) is a conserved mitotic regulator that preserves genome stability by monitoring kinetochore–microtubule attachments and blocking anaphase onset until chromosome biorientation is achieved. Despite its central role in maintaining mitotic fidelity, the ability of th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014101/ https://www.ncbi.nlm.nih.gov/pubmed/29688794 http://dx.doi.org/10.1091/mbc.E18-04-0215 |